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Re: ISO vs GMP

Michael:

Your subject line: ISO vs GMP may be designed to be provocative, 
suggesting that these two standards compete, one with the other, for 
a common customer base. I suspect that I am rising to your bait!

Bait or not, ISO 9000 series quality standard represents a baseline 
for anyone who may have an interest in 'quality' as the underpinnings 
of their business growth/improvement.

While there may be no regulatory reason to become ISO 9001 certified 
if one is GMP compliant, I do believe that sort of thinking sends the 
wrong message. It may, for example, send the message that quality is 
only important if a regulator has required it. In the case of ISO 
standards, and by way of example, the 13000 and 14000 series would 
apply.

There are, in addition, national quality standards in play, such as 
Congress-endorsed Baldridge in the USA (Canada, Australia and the EU 
have similar government endorsed arrangements) which have similar 
goals to those standards of the ISO but do more, such as aims across 
corporate structures via -a- vis improvement, performance/outcomes 
measures to standardize those elements of business process 
improvements directed,or amenable to, society standards of 
performance. The message here is that CORPORATE (as opposed to 
Division/Department) quality pursuits can be shown to make a 
significant contribution to corporate financial health, or any other 
similar yardstick, no matter what your business is.

I can, therefore, certainly suggest that a manufacturing business 
entity that is GMP compliant would also benefit from the pursuit of 
Baldridge, if located in the USA, or some other similar national 
standard with Baldridge-like aims. One or more of these groups have 
published data in an effort to show how compliance ( to their 
requirements) goes straight to the 'bottom line'.

Many of these multiple standards embrace elements which are akin to 
one another. Government has acknowledged this in their incorporation 
into law of ISO 13000 series standards for medical devices 
regulations and 14000 series standards for environmental compliance.

Is GMP compliance important? Yes. Why is it important? Because it is 
the law? Or because, if followed, the outcome is a safe and effective 
product? The latter I hope. GMP does not as much for effective 
processes in HR, Communications, Finance, Controller, Accounts 
Payable, Accounts Receivable, Legal, Premises (other than 
manufacturing),Investor Relations, etc. If you have a totally 
compliant manufacturing/QC group....great....but that alone will not 
necessarily make you (the organization) the best that you can be in 
terms of financial performance that all of us require.

Kind regards

J. W. Rees


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