Pavel,
You will find what you require in the first paragraph of the following
paper:
M.D. Hollenberg, Receptor Binding and Agonist Efficacy: New Insights from
Mutants of the Thrombin Protease-Activated Receptor-1 (PAR-1). Mol.
Pharmacol. 2000; 58:1175-1177.
Walter Sneader
_________________________________________
Dr Walter Sneader,
Head of the School of Pharmacy,
University of Strathclyde,
The John Arbuthnott Building,
27 Taylor Street,
Glasgow G4 ONR,
United Kingdom.
tel: +44 141 548 2155
fax: +44 141 552 6443
e-mail: w.e.sneader@strath.ac.uk
-----Original Message-----
From: History@www2.pharmweb.net [mailto:History@www2.pharmweb.net]On
Behalf Of Pavel Muller (by way of Greg Higby)
Sent: 28 July 2003 22:03
To: History
Subject: History of the dose-response relationship
Dear colleagues,
I am putting together a review of human health risk assessment and I would
like to include a paragraph or so about the history of dose-response curve.
I am a pharmacologist by training and dose-response is thus close to my
heart, but I know little about its history. I need quotable material, if
possible. Can you help?
Pavel
__________________________
Pavel Muller, Ph.D.
President, ToxProbe Inc.
215, Wynford Drive # 1801
Toronto, Ontario M3C 3P5
Canada
tel.: (416) 467-5106
fax: (416) 423-8276
pavelmuller@toxprobe.com
Web: www.toxprobe.com
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