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En: [farmacia] En: PharmCare Digest - 02/16/00


-----Mensagem original-----
De: CIMUFC <cimufc@ufc.br>
Para: <farmacia@cff.org.br>
Cc: Lista da pharmanet <farmacia@egroups.com>
Data: Quarta-feira, 16 de Fevereiro de 2000 11:38
Assunto: Re: [farmacia] En: PharmCare Digest - 02/16/00


FYI:

Health professionals are notified of the possibility of drug
nteractions between St. John's Wort (hypericum perforatum), an herbal 
product sold
as a >dietary supplement, and indinavir, a protease inhibitor used to treat
HIV infection.  A study conducted by the National Institutes of Health
showed that a significant drug interaction substantially decreased indinavir
plasma concentrations, potentially due to induction of the cytochrome P450
metabolic pathway.  For a copy of the Public Health Advisory see:
>http://www.fda.gov/cder/drug/advisory/stjwort.htm
>
>MedWatch
>
>Pablo A. Pereira escreveu:
>
>>  -----Mensagem original-----
>>  De: <ghafari@nova.edu>
>>  Para: PharmCare <PharmCare@pharmweb1.man.ac.uk>
>>  Data: Quarta-feira, 16 de Fevereiro de 2000 06:05
>>  Assunto: PharmCare Digest - 02/16/00
>>
>>  >Does anyone know of the interaction between Saint John's Wort and the
>>  >protease inhibitors?
>>  >
>>  >R.G. ghafari@nova.edu
>>  >
>>  >
>
>
>
>
>


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