[Date Prev][Date Next][Thread Prev][Thread Next]
Author IndexDate IndexThread Index

Drug Alert - USA - FDA report dated 9 April 1997

RECALLS AND FIELD CORRECTIONS:  DRUGS -- CLASS II ===========
_______________
PRODUCT        (a) Transfilled Medical Oxygen in D, E, J, MPs
               and K cylinders; (b) Liquid Medical Oxygen.
               Recall #D-132/133-7.
CODE           All codes, all lots, and all fill dates.
MANUFACTURER   Lewin Agency, Inc., doing business as Lewin
               Medical Supply, Riverhead, New York.
RECALLED BY    Manufacturer, by telephone on March 18, 1997,
               followed by letter.  Firm-initiated recall
               ongoing.
DISTRIBUTION   New York.
QUANTITY       132 cylinders and 2 31-liter cryogenic vessels
               were distributed.
REASON         Current good manufacturing practice
               deficiencies (FDA inspection found that
               product was not tested for strength and the
               oxygen analyzer was not properly maintained).

_______________
PRODUCT        Clindamycin Phosphate Injection, USP, 150
               mg/ml, Rx small volume parenteral
               semisynthetic antibiotic for IV or IM
               administration for the treatment of serious
               infections caused by susceptible anaerobic
               bacteria; packaged in 2 ml, 4 ml and 6 ml
               single dose vials, 25 vials per box.
               Recall #D-137-7._CODE           Catalog 22602, 2 ml fill in 2 ml vial,
               Catalog 22604, 4 ml fill in 5 ml vial,
               Catalog 22606, 6 ml fill in 10 ml vial.
               Lot numbers 951067, 951069, 951222, 951235,
               960639, 951040, 951084, 951146, 960126, 960618
MANUFACTURER   SoloPak Pharmaceuticals Inc., Elk Grove
               Village, Illinois.
RECALLED BY    Manufacturer, by letter dated March 13, 1997.
               Firm-initiated recall ongoing.
DISTRIBUTION   Nationwide.
QUANTITY       320,000 vials were distributed; firm estimated
               that 1 percent of product remained on market
               at time of recall initiation.
REASON         Bulk Clindamycin was recalled by Roussel
               Corporation (parent firm of Biochimica Opos)
               due to AADA discrepancies regarding the
               manufacturing process; AADA was withdrawn.

_______________
PRODUCT        Clindamycin Phosphate Injection, USP sterile
               solution (150mg/ml) in 2ml, 4ml, 6ml, and 60ml
               single dose containers (SDC) which are
               packaged 25 SDCs per intermediate carton, a
               prescription drug given intramuscularly or
               intravenously for the treatment of serious
               infections caused by susceptible anaerobic
               bacteria.  Recall #D-138-7.
CODE           (2ml) Lot Nos. 1450605038, 1450608035.
               (4ml) Lot Nos. 1451509066, 1451601040,
               1451603105, 1451605035, 1451606048,
               1451609805, and 1451609806.
               (6ml) Lot Nos. 1452509065, 1452603109,
               1452605033, 1452606051, and 1452609804.
               Lot Nos. 1453510021, 1453601100 and
               1453610040.
MANUFACTURER   Astra USA Inc. Westboro, Massachusetts.
RECALLED BY    Manufacturer, by letter dated March 20, 1997.
               Firm-initiated recall ongoing.
DISTRIBUTION   Nationwide.
QUANTITY       47,757 saleable units were distributed; firm
               estimated that 3,100 units of product shipped
               prior to January 31, 1997, were still in
               distribution at time of recall initiation.
REASON         Bulk Clindamycin was recalled by Roussel
               Corporation (parent firm of Biochmicia Opos)
               due to AADA discrepancies regarding the
               manufacturing process; AADA was withdrawn.

_______________
PRODUCT        Phenytoin Oral Suspension, USP packaged in
               unit dose cups and oral syringes, Rx oral
               antiepileptic drug, unit dose cups are
               packaged 10 cups per tray, with 5 or 10 trays
               per case, 100 mg 4-ml unit dose cup, 50
               cups/case; 100 mg 4-ml unit dose cup, 100
               cups/case; 100 mg 4-ml oral syringe, 50
               syringes/case; 300 mg 12-ml unit dose cup, 100
               cups/case.  Recall #D-140-7.
 CODE          All lots within expiration date -- 605609,
               604610, 603614, 603613, 603601, 602802,
               602606, 602605, 601612, 601614, 512609,
               512604, 512606, 512607, 512603, 511606,
               511605, 510604, 510606, 510607, 509612,
               509607, 509606, 509612.
MANUFACTURER   Parke-Davis, Division of Warner-Lambert
               Company, Morris Plains, New Jersey.
RECALLED BY    Xactdose, Inc., South Beloit, Illinois
               (repacker), by letter dated March 4, 1997.
               Firm-initiated recall ongoing.
DISTRIBUTION   Nationwide.
QUANTITY       6,116 cases of 50/4 ml cups, 15,372 cases of
               100/4 ml cups, 174 cases of 100/12 ml cups,
               and 116 cases of 50/4 ml oral syringes were
               distributed; firm estimates that little, if
               any, product remains on the market.
REASON         Product failed content uniformity test.


RECALLS AND FIELD CORRECTIONS:  DRUGS -- CLASS III ==========
_______________
PRODUCT        Dexamethasone Sodium Phosphate for Injection,
               USP, 10 mg/ml, in 10 ml multi-dose vials,
               sterile, injectable glucocorticoid, under the
               following labels:  Steris, Schein, Clint, and
               Robar.  Recall #D-136-7.
CODE           LOT      EXPIRATION
               95E710    7/97
               95F530    9/97
               95K460   11/97
               95L190   11/97
               95L770   12/97
               96C420    3/98
               96H430    7/98.
MANUFACTURER   Steris Laboratories, Inc., Phoenix, Arizona.
RECALLED BY    Manufacturer, by letter dated January 27,
               1997.  Firm-initiated recall ongoing.
DISTRIBUTION   Nationwide, Puerto Rico, Peru.
QUANTITY       Approximately 94,500 vials were distributed.
REASON         Product failed pH specification (SPEC is 7.0-
               8.5pH); actual is 8.6.

_______________
PRODUCT        Trisoralen Tablets, 5 mg. (Trioxsalen, USP),
               packaged in bottles of 28 tablets and 100
               tablets, (bottles of 10 and 1000 were
               exported), a prescription drug for oral
               administration and is indicated for the
               repigmentation of idiopathic vitiligo; for
               increasing tolerance to sunlight and for
               enhancing pigmentation.  Recall #D-139-7.
CODE           All lot numbers (18 total) within expiration
               date are under recall.  The lot numbers and
               expiration dates which identify domestic, and
               possibly, foreign distribution are: E0216
               (2/97), E0503 (5/97), E1107 (11/97), E1124
               (12/97), F0102 (2/98), F0219 (3/98), F0408A
               (5/98), F0408B (5/98), F1217B (1/99), F1217B
               (1/99), G0816A (9/99), G0816B (9/99), G1001A
               (11/99), G1001B (11/99), H0321A (5/00), H312B
               (5/00), H0831A (9/98), H1122B (12/98).
               The lot numbers which exclusively identify
               international distribution are:  E1228,
               F0403A, F0403B, F0219E, F0408AE, F0408BE,
               F0801A, F0801B, H0831B, & H1122A.
MANUFACTURER   ICN Pharmaceuticals, Inc., Inc., Costa Mesa,
               California (responsible firm).
RECALLED BY    ICN Pharmaceuticals, Inc., Bryan, Ohio, by
               letter dated February 25, 1997.  Firm-
               initiated recall ongoing.
DISTRIBUTION   Nationwide and international.
QUANTITY       58,514 bottles were shipped to domestic
               accounts.
REASON         Product fails dissolution test requirements
               (SPEC is NLT 75%; actual is as low as 45%).



Alan W Davidson
General Secretary, International Pharmaceutical Federation
a.davidson@fip.nl or visit our web site at
http://www.pharmweb.net/pwmirror/pw9/fip/pharmweb92.html



[Date Prev][Date Next][Thread Prev][Thread Next]
Author IndexDate IndexThread Index