LIST OF POSTERS

A: Physicochemical Aspects of Drug Action: Po-1 - Po-20

B: Dosage Form Design: Po-21 - Po-89

C: Drug Analysis: Po-90 - Po-138

D: Natural Product Chemistry and Phytotherapy: Po-139 - Po-172

E: PK/PD and Toxicology: Po-173 - Po-211

F: Drug Design and Development: Po-212 - Po-261

G: Regulatory, Validation and Other Issues: Po-262 - Po-271

A: Physicochemical Aspects of Drug Action: Po-1 - Po-20

Po-1 Demopoulos, I. Nicolaou, N. Zaher and Ch. Zika (Thessaloniki, Greece): A QSAR Study on a Set of Antiinflammatory Pyrrolamines

Po-2 A. Göblyös, T. Martinek, L. Lázár and F. Fülöp (Szeged, Hungary): Ring-Chain Tautomerism of Hexahydropyrimidines

Po-3 M. Józan (Budapest, Hungary): Standardized Method for the Solubility Characterization of Pharmaceutics

Po-4 M. Józan, J. Kökösi and I. Hermecz (Budapest, Hungary): Experimental and Calculated (PM3) Dipole Moments for Nitrogen Bridgehead Heterocyclic Compounds

Po-5 M. Józan, V.J. Stella, S.L. Gupta and B.R. Vishnuvajjala (Budapest, Hungary - Lawrence, USA - Bethesda, USA): Lactone Ring Hydrolysis of Camptothecin Analogues

Po-6 K. Kóczián, K. Mazák, M. Kata and B. Noszál (Budapest, Hungary): Acid-Base Properties of Tenoxicam, a Non-Steroidal Anti-Inflammatory Agent

Po-7 Zs. Kovács and B. Noszál (Budapest, Hungary): Ester Hydrolysis Kinetics of Tropane-Derivative Alkaloids

Po-8 M. Kraszni and B. Noszál (Budapest, Hungary): Conformer-Specific Partition: Theory and Application to Flexible Drugs

Po-9 M. Kraszni and B. Noszál (Budapest, Hungary): Rotamer Populations of Ephedrine and Pseudoephedrine

Po-10 M. Kraszni, D. Visky and B. Noszál (Budapest, Hungary): Rota-Microspeciation of Histamine

Po-11 M. Maldonado, J.M.Lawrence and A.F. Drake (London, UK): The Determination of pKa and Cyclodextrin-Drug-Binding Complex Constants by UV and CD Titrations

Po-12 K. Mazák, A. Nemes and B. Noszál (Budapest, Hungary): Proton Speciation and Microspeciation of Vinpocetine and Related Compounds in Aqueous and Biomimetic Media

Po-13 K. Monostory, P. Perjési and L. Vereczkey (Budapest, Hungary - Pécs, Hungary): Study on CYP1A Inhibitory Action of E-2-(4'-methoxybenzylidine)-benzosuberone and Some Related Cyclic Chalcone Derivatives

Po-14 P. Perjési, E. Ösz, J. Vámos and K. Takács-Novák (Pécs, Hungary - Budapest, Hungary): Structure-Lipophilicity Study of Biologically Active Cyclic Chalcone Derivatives

Po-15 M. Plass, I. Wawer, K.Valkó and M.H. Abraham (Halle, Germany - Warsaw, Poland - Stevenage, UK - London, UK): Effect of Intramolecular Hydrogen Bonding on the Predictability of QSAR Descriptors

Po-16 Á. Rácz, M.Józan and B. Noszál (Budapest, Hungary): Quantum Chemical Parameters of Glutamic Acid Rotamer Population

Po-17 K. Takács-Novák and P. Nagy (Budapest, Hungary - Toledo, USA): Experimental and Theoretical Study on Ion-pair Formation and Partition

Po-18 K.Y. Tam and K. Takács-Novák (Forest Row, UK - Budapest, Hungary): Interlaboratory Validation Study on Multiwavelength Spectrophotometric pKa Determination

Po-19 D. Visky, M. Kraszni and B. Noszál (Budapest, Hungary): Characterisation of Ester Hydrolysis in Terms of Microscopic Rate Constants

Po-20 D. Visky, M. Kraszni and B. Noszál (Budapest, Hungary): Population, Acid-Base and Redox Properties of N-Acetyl-cysteine Rotamers

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B: Dosage Form Design: Po-21 - Po-89

Po-21 S.I. Abdel-Rhaman, A.A. Abdel-Rhaman, S.H. Khidr, A. Ismail and G.M. Soltan (Assiut, Egypt): Preparation and Characterization of Azapropanone - 2-Hydroxypropyl-b-Cyclodextrin Inclusion Complexes and their Effect on Drug Release from Gel Bases

Po-22 Z. Aigner, M. Kata, Á. Kézsmárki, Cs. Novák, K. Sütö, I. Csóka and I. Erös (Szeged, Hungary - Budapest, Hungary): Investigation of Tenoxicam + g-Cyclodextrin Complexes

Po-23 Z. Aigner, M. Kata, E. Szepesi and Cs. Novák (Szeged, Hungary - Budapest, Hungary): Investigation of Ethacrynic Acid - Cyclodextrin Complexes

Po-24 B. Arica, S. Calis, I. Vural, S. Kas, F. Kumbaradzi and A.A. Hincal (Ankara, Turkey - Skopje, Macedonia): 5-FU Loaded PLGA Microspheres Blended with Chitosan Gel for Local Application in Breast Cancer: Formulation and In Vitro Release Profiles

Po-25 J. Bajdik, K. Pintye-Hódi, P. Szabó-Révész, P. Kása jr. and I. Erös (Szeged, Hungary): Testing and Coating of Dimenhydrinate Crystals

Po-26 S.E. Bartsch, V. Stingl and A. Burger (Innsbruck, Austria): Investigation of the Layering Mechanism of Fluid-Bed Melt Granulation by Scanning Electron Microscopy (SEM)

Po-27 A. Bediz-Ölcer, N. Gönül and I.T. Degim (Ankara, Turkey): Penetration Properties of Etodolac through Rabbit and Rat Skin

Po-28 Á. Beretzky, K. Pintye-Hódi, P. Szabó-Révész, P. Kása jr. and I. Erös (Szeged, Hungary): Preparation of Lithium Carbonate Pellets with a Centrifugal Granulator

Po-29 Sz. Berkó, G. Regdon jr. and I. Erös (Szeged, Hungary): Study of Drug Release from Suppositories with Modern Additives Used

Po-30 G.P. Bettinetti, M.T. Faucci, P. Mura, M. Sorrenti, A. Tolokán and Cs. Novák (Pavia, Italy - Florence, Italy - Budapest, Hungary): Preformulation Study of Naproxen - Methyl-b-Cyclodextrin Peroral Solid Preparations

Po-31 Z. Budavári, R. Zelkó, G. Csóka, R. Fekete, E. Farkas, I. Antal, I. Rácz and S. Marton (Budapest, Hungary): Preformulation Study of Tablets Containing Vitamin B6, B12 and Folic Acid

Po-31/A M. Burjak, P. Verzun, M. Bogataj and A. Mrhar (Ljubljana, Slovenia): The Influence of Chitosan/Polycarbophil Ratio on the Adhesion of Microspheres on Pig Vesical Mucosa

Po-32 N. Celebi, A. Türkyilmaz, N. Gökcora and B. Gönül (Ankara, Turkey): Investigation of the Effects of Different EGF Formulations on Healing of Acute Gastric Ulcers

Po-33 E.O. Cetin, S. Sahin and A.A. Hincal (Ankara, Turkey): In Vitro Characterization of Chlorpromazine Hydrochloride Uptake by Human Erythrocytes: Effect of Concentration and Hematocrit

Po-34 O.I. Corrigan and A.M. Crean (Dublin, Ireland): Preparation and Characterization of Drug-PVP Dispersions Prepared Using Carbon Dioxide by the Gas Antisolvent Recrystallization Process

Po-35 E. Csányi, I. Erös, M. Makai and I. Csóka (Szeged, Hungary): Emulsions as Controlled Drug Delivery Systems: 3. Study of Microemulsions

Po-36 I. Csóka, I. Erös, T. Kövér, K. Sütö, E. Csányi and M. Makai (Szeged, Hungary): Emulsions as Controlled Drug Delivery Systems: 2. Study of Multiple Emulsions

Po-37 E. Cumbul, F. Öner and S. Kas (Ankara, Turkey): Hemoglobin Loaded Chitosan Microspheres as Blood Substituents

Po-38 I.T. Degim and F. Acartürk (Ankara, Turkey): Penetration Properties of Bromocriptine Mesylate from Gel Formulations across Rabbit Skin

Po-39 Gy. Dékány, I. Csóka, I. Erös and I. Dékány (Szeged, Hungary): In Vitro Release Evaluation of Steric Stabilized Liposomes

Po-40 A. Dévay (Budapest, Hungary): Investigation of Parameters Determining Structure of Liposomes

Po-41 I. El-Gibaly and M. Fathy (Assiut, Egypt): Development and Evaluation of Verapamil Resinates-Loaded Controlled Release Microcapsules Using a Binary Polymer System in Drug Release Rate Modulation

Po-42 I. Erös, T. Kövér, A. Cserne, I. Csóka, E. Csányi and M. Makai (Szeged, Hungary): Emulsions as Controlled Drug Delivery Systems: 1. Study of Macroemulsions

Po-43 J.B. Farina, J.T. García and M. Llabrés (La Laguna, Tenerife, Spain): Controlled Release of Recombinant Human Growth Hormone from Biodegradable Film Implants

Po-44 E. Farkas, R. Zelkó, T. Horányi, R. Fekete, G. Csóka, I. Antal, Z. Budavári, I. Rácz and S. Marton (Budapest, Hungary): Drug Release Examination of Liquid Crystalline Gels in Relation to the Structure and Mechanical Properties

Po-45 I. Fejér, M. Kata, I. Erös and I. Dékány (Szeged, Hungary): The Role of Montmorillonite in Retard Formulations

Po-46 R. Fekete, I. Antal, E. Farkas, G. Csóka, R. Zelkó, Z. Budavári, I. Rácz and S. Marton (Budapest, Hungary): Application of Near Infrared Spectroscopy for the Determination of Coating Thickness

Po-47 N. Fotaki, M. Vertzoni, J.B. Dressman and C. Reppas (Athens, Greece - Frankfurt, Germany): Optimizing the In Vitro Conditions to Simulate the Release Process in Stomach after Meals

Po-48 E. Fredro-Kumbaradzi and M. Glavas-Dodov (Skopje, Macedonia): Some Formulation Aspects of Drug Release from Multiple W/O/W Emulsion

Po-49 O.L. Freichel and B.C. Lippold (Düsseldorf, Germany): The Mechanism of Release Progression from Methylhydroxy Ethylcellulose Tablets Containing Enteric Coating Materials as Additives

Po-50 Á. Gombás, P. Szabó-Révész, M. Hasznos-Nezdei, K. Pintye-Hódi and I. Er‘s (Szeged, Hungary - Veszprém, Hungary): Study of Interaction between Sorbitol and Citric Acid by Thermoanalytical Methods

Po-51 H. Göczö, P. Szabó-Révész, B. Farkas, M. Hasznos-Nezdei, S. Serwanis, K. Pintye-Hódi, I. Erös, I. Antal and S. Marton (Szeged, Hungary - Budapest, Hungary - Veszprém, Hungary): Development of Spherical Crystals of Acetylsalicylic Acid

Po-52 M. Hellemann, U.J. Griesser, Th. Abberger and A. Burger (Innsbruck, Austria): Bulk Properties and Consolidation Behavior of Caffeine Polymorphs

Po-53 S. Honary, A. Majidian and M. Chaygani (Sari, Iran): A Study of the Role of Particle Size, Shape and Quantity of Solid Powders on the Spreadability of Semisolids

Po-54 P. Kaclík, T. Fazekas and M. Vitková (Bratislava, Slovakia): Regression Models of the Liberation Kinetics of Lithium Carbonate from the Solid Drug Forms

Po-55 E. Karasulu and B. Gulec (Izmir, Turkey): Preparation of Ketoconazole Buccal Tablet for Oral Cavity

Po-56 H.Y. Karasulu, F. Taneri, E. Sanal, G. Ertan and T. Güneri (Izmir, Turkey): Ketoconazole Microcapsules Tabletted for Vaginal Delivery, Preparation, Micromeritic, Dissolution and Microbiological Studies

Po-57 A. Karatas and T. Baykara (Ankara, Turkey): Studies on Release of Indomethacin and Ketorolac Tromethamine from Inserts Prepared Using Hydrogels

Po-58 P. Kása, K. Pintye-Hódi, P. Szabó-Révész, I. Erös and P. Kleinebudde (Szeged, Hungary-Halle, Germany): Preparation of Diclofenac Sodium Containing Pellets with Centrifugal Granulator

Po-59 M. Kata, D. Gyökér, Z. Aigner, Cs. Novák and I. Erös (Szeged, Hungary - Budapest, Hungary): Study of Piroxicam and Cyclodextrin Inclusion Complexes

Po-60 M. Kata, I. Dufka, L. Sebök, Z. Aigner and I. Erös (Szeged, Hungary): Surface Tension and Partition Coefficients of CD-Complexes

Po-61 B.U. Killen and O.I. Corrigan (Dublin, Ireland): The Effect of Fatty Acid Type on Drug Release from Drug Fatty Acid Compacts

Po-62 M. Makai, E. Csányi, I. Erös, I. Dékány, J. Pálinkás and Zs. Németh (Szeged, Hungary - Budapest, Hungary): Characterisation of Lyotropic Liquid Crystals as Drug Delivery Systems

Po-63 E. Memisoglu, A. Bochot, D. Charon, A.A. Hincal and D. Duchene (Ankara, Turkey - Chatenay-Malabry, France): Characterization of Nanoparticles Composed of Amphiphilic Beta-Cyclodextrins Modified on the Primary Face

Po-64 K. Mladenovska, K. Goracinova, K. Zafirova and E. Janjevic (Skopje, Macedonia): Influence of Processing Variables on the Microencapsulation Efficacy and Particle Size of Crosslinked Gelatine Microspheres

Po-65 K. Mladenovska, Lj. Klisarova and K. Goracinova (Skopje, Macedonia): Fourier-Transform Infrared Spectroscopic Studies of the Secondary Structure of Bovine Serum Albumin

Po-66 K. Orosz, I. Erös, T. Kövér, A. Cserne, I. Csóka and E. Csányi (Szeged, Hungary): Emulsions as Controlled Drug Delivery Systems: 4. Study of Gel-Emulsions

Po-67 Ö. Özer, Özyazici, E. Baloglu and S. Hizarcioglu (Izmir, Turkey): The Effect of Urea and DMSO on the In Vitro Diffusion of Metronidazole from W/O and O/W Emulsions

Po-68 G. Pifferi, M. Provezza and R. Schrepfer (Milano, Italy - Campocologno, Switzerland): Development of a Freeze-dried Injectable Form of Tiaprofenic Acid

Po-69 F. Pour-Morad, S. Honary and A.H. Jiani (Sari,Iran): A New Formulation for Povidone-Iodine

Po-70 G. Regdon jr., K. Hódi, P. Kása jr., P. Révész, I. Erös and P. Kleinebudde (Szeged, Hungary - Halle, Germany): Enteric Solvent Film Coating of Pellets Containing Diclofenac Sodium

Po-71 H.M. Ribeiro, S. Quinta, D. Campos, P. Pinto, J. Morais and L. Rodrigues (Lisbon, Portugal): About the Biological Interest of Polymers for Skin Care Formulation

Po-72 R. Rodríguez, C. Álvarez-Lorenzo and A. Concheiro (Santiago de Compostela, Spain): Polyquaternium-4 and Polyquaternium-10: Rheological Evaluation of their Aqueous Dispersions and Mixtures with Carbopol 974P

Po-73 M. Säkkinen, P. Veski and M. Marvola (Helsinki, Finland - Tartu, Estonia): A Controlled Release Formulation Containing Microcrystalline Chitosan as a Gel-forming Excipient and its Performance In Vivo

Po-74 O. Salmela, H. Sepps, S. Eeriksinen, M. Marvola and R. Tuominen (Helsinki, Finland): Bioavailability of Ibuprofen from Rectally and Orally Administered Hydroxypropyl Methylcellulose Capsules Compared to Gelatine Capsules

Po-75 M.K. Samanta, R. Dube and B. Suresh (Ooty, India): A Novel Formulation of Transdermal Film Containing Haloperidol-loaded Microspheres to Overcome Self-induced Extrapyramidal Syndrome

Po-76 T. Schmidt-Mende, C.S. Leopold and B.C. Lippold (Düsseldorf, Germany): Drug Diffusion through Films of Enteric Coating Materials - Comparison of Free Films with Film-coated Mini Tablets

Po-77 G. Shlieout, R. Lammens, F. Wöll, R. Grulke and P. Kleinebudde (Leverkusen, Germany - Halle, Germany): Dry Granulation of Lactose with a Gerteis 3-W-Polygran Roller Compactor: Analysis of Process Data

Po-78 E. Sipos, A. Popovici, E. Soós-Csányi and I. Erös (Targu Mures, Romania - Szeged, Hungary): Concentration Influence on the Viscosity of Different Carbopol Gels

Po-79 G. Stampf, M. Jelinek-Nikolics and I. Horváth (Budapest, Hungary): Formulation and Investigation of a Parenteral Dosage Form Containing Trimethoprim

Po-80 A. Szalay, K. Pintye-Hódi, P. Szabó-Révész, P. Kása jr. and I. Erös (Szeged, Hungary): Determination of Shape Factors of Particles with an Image Analysis System

Po-81 N. Tarimci and T. Kilinc-Sen (Ankara, Turkey): Optimisation of Gel Formulations of Retinoic Acid - b-Cyclodextrin Complexation

Po-82 A. Trojak, O. Planinsek and S. Srcic (Ljubljana, Slovenia): Prediction of Optimum Binder with Spreading Coefficient Values

Po-83 M. Vitková, J. Rak, M. Chalabala and J. Dvoráková (Bratislava, Slovakia): Theophylline in a Peroral CR Drug Form

Po-84 E. Vranic, S. Hadzovic and A. Mehmedagic (Sarajevo, Bosnia and Herzegovina): Evaluation of Mathematical Discriminatory Tools for Dissolution Testing

Po-85 I. Vural, S. Calis, B. Arica, S. Kas, F.Kumbaradzi and A.A. Hincal (Ankara, Turkey - Skopje, Macedonia): Formulation and In Vitro Characterization of Chitosan Treated 5-FU Liposomes for Local Application in Breast Cancer

Po-86 K. Welin-Berger, J. Neelissen and B. Bergenstahl (Södertälje, Sweden - Lund, Sweden): The Effect of Rheological Behavior of the Formulation on the Release and Permeation Rate of the Active Substance

Po-87 I. Yenice, S. Calis, S. Kas, M. Özalp, M. Ekizoglu and A.A. Hincal (Ankara, Turkey): Teicoplanin, a Glycopeptide Antibiotic: Stability and Microbiological Evaluation

Po-88 R. Zelkó, F. Kiekens, J.P. Remon and K. Süvegh (Budapest, Hungary - Gent, Belgium): Effects of Storage Conditions on the Physical Aging of Polyvinylpyrrolidone: Comparison of Enthalpy Relaxation and Positron Lifetime Data with the Tensile Strength of Tablets

Po-89 Zs. Zsigmond, I. Antal, P. Fekete, I. Rácz and S. Marton (Budapest, Hungary): Application of Reflectance Spectroscopy in the Control of Potassium Chloride Containing Pellet Preparation

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C: Drug Analysis: Po-90 - Po-138

Po-90 G. Altiokka, Z. Atkosar and M. Tuncel (Eskisehir, Turkey): Polarographic Determination of Meloxicam in Pharmaceutical Preparations

Po-91 K. Ary and K. Róna (Budapest, Hungary): Validated HPLC Method for the Determination of Morphine and its Glucuronide Metabolites in Human Plasma by Coulometric and UV Detection

Po-92 Z. Atkosar, G. Altiokka, Z. and M. Tuncel (Eskisehir, Turkey): The Determination of Enoxacin in Tablets by Potentiometry and Conductometry

Po-93 A. Benecchi, A. Pouwels, N.C. van de Merbel and C.A. James (Nerviano, Italy - Assen, The Netherlands): Determination of Exemestane in Human Plasma by HPLC and Tandem Mass Spectrometric Detection

Po-94 J. Bertram (Berlin, Germany): Multisource Pharmaceutical Bulkware-Methods for Profiling and Structural Elucidation of Impurities

Po-95 E. Bodoki, R. Oprean, M. Tamas and R. Sandulescu (Cluj-Napoca, Romania): Quick and Simple Thin-Layer Densitometric Determination of Colchicine

Po-96 S. Bozdag, S. Calis and M. Sumnu (Ankara, Turkey): Validation of an HPLC Method for the Determination of Omeprazol

Po-97 E. Castellanos Gil, A. Van Schepdael, E. Roets and J. Hoogmartens (Havana, Cuba - Leuven, Belgium): Analysis of Doxycycline by Capillary Electrophoresis. Method Development and Validation

Po-98 S.M. Cetin and Z. Aydogmus (Istanbul, Turkey): Determination of Ascorbic Acid in Vegetables and Soft Drinks by Derivative Spectrophotometry

Po-99 H.K. Chepkwony, E. Roets and J. Hoogmartens (Leuven, Belgium): Liquid Chromatography of Troleandomycin

Po-100 V. David, J.V. García Mateo and J. Martínez Calatayud (Bucharest, Romania - Valencia, Spain): On-Line Photochemical Reaction - Chemiluminescent Detection: a Sensitive Approach for Pharmaceutical Analysis

Po-101 A. Dimitrovska, Lj. Ugrinova, S. Trajkovic-Jolevska and S. Tanceva (Skopje, Macedonia): Infrared Spectroscopic Identification of the Components in Plastic Containers, Blister Packing and Rubber Closures

Po-102 S. Erturk, E.S. Aktas and S. Atmaca (Istanbul, Turkey): High-Performance Liquid Chromatographic Analysis of Vigabatrin in Human Plasma with Fluorescence Detection

Po-103 R. Ficarra, M.L. Calabró, S. Tommasini, S. Melardi, P. Cutroneo and P. Ficarra (Catanzaro, Italy - Messina, Italy): Direct Enantiomeric Separation of Reboxetine by Liquid Chromatography Using Different Cellulose and Amylose Based Chiral Stationary Phases

Po-104 R. Ficarra, D. Raneri, S. Tommasini, M.L. Calabró, M.R. Di Bella and P. Ficarra (Catanzaro, Italy - Messina, Italy): Structural and Thermodynamic Study of b-Blockers /b-Cyclodextrin Inclusion Complexes

Po-105 B.H. Forngren, N. Tyrefors, K.E. Markides and B. Langström (Uppsala, Sweden): Determination of Raclopride in Human Plasma by On-Column Focusing Packed Capillary Liquid Chromatography - Electrospray Ionisation - Mass Spectrometry

Po-106 Y. Fuster, L. Lahuerta and J. Martínez Calatayud (Valencia, Spain): Determination of Quinolones in a FIA System Endowed with a Solid-Phase Reactor as Reagent Source

Po-107 O. Gyllenhaal (Mölndal, Sweden): Fast Enantioresolution of Clevidipine and a Dihydropyridine Substituted Acid by SFC on Chiralpak A

Po-108 O. Gyllenhaal, S. Andersson, J. Forsgard, J. Hulthe, A. Karlsson, P. Owens, S. Svensson, J. Vessman and K. Öhlén (Mölndal, Sweden): Packed Column SFC of Enantiomeric Drugs on Various Chiral Columns

Po-109 O. Gyllenhaal, A. Karlsson and J. Vessman (Mölndal, Sweden): Packed Column SFC in the Development of Drugs with the Emphasis on the Purity of Bulk Drug Substances

Po-110 Á. Gyéresi, M. Péter and F. Fülöp (Targu Mures, Romania - Szeged, Hungary): Liquid Chromatographic Enantioseparation of Beta-blocking Agents with a New Isothiocyanato-type Derivatizing Agent

Po-111 K. Gyimesi-Forrás, Gy. Szász and J. Kökösi (Budapest, Hungary): Chiral Liquid Chromatographic Separation of New Potential Cholecystokinin Antagonist Nitrogen-Bridgehead Heterocycles

Po-112 B. Hegedžs (Budapest, Hungary): What is the Optimal Power of the Irradiating Beam at an FT-Raman Examination?

Po-113 T. Hinrikus and K. Utsal (Tartu, Estonia): Investigation of Antibiotic Dosage Forms by X-Ray Diffraction Method

Po-114 E. Kaale, S.Leonard, A. Van Schepdael, E. Roets and J. Hoogmartens (Leuven, Belgium): Capillary Electrophoresis Analysis of Gentamicin with UV Detection after Pre- Capillary Derivatization with 1,2-Phthalic Dicarboxaldehyde and Mercaptoacetic Acid

Po-115 J.W. Kang, A. Van Schepdael, E. Roets and J. Hoogmartens (Leuven, Belgium): Analysis of Polymixin B Sulfate by Capillary Zone Electrophoresis with Cyclodextrin as Additive. Method Development and Validation

Po-116 M. Mák, G. Balogh, G. Czira, Zs. Skribanek, J. Széles, Zs. Halmos, S. Mahó and S. Görög (Budapest, Hungary): Complex Mass Spectrometric Methods in the Identification of Drug Impurities

Po-117 H.R.N. Marona and E.E.S. Schapoval (Araraquara - Porto Alegre, Brazil): Analysis of Sparfloxacin and its Degradation Products by Bioassay

Po-118 J. Martínez Calatayud, M. Catalá Icardo, O. Armenta Estrela, M. Sayewicz and J.V. García Mateo (Valencia, Spain - Bialystok, Poland): Flow Injection Biamperometry: a Selective Approach for Amino Acid Determination

Po-119 M.T. Maya, N.E. Silva, N.J. Goncalves and J.G. Morais (Lisbon, Portugal): A Simple HPLC Method for the Determination of Ciprofloxacin in Human Plasma

Po-120 K. Mazák, Z. Szakács, A. Nemes and B. Noszál (Budapest, Hungary): Capillary Electrophoresis Separation of Vinpocetine and Related Compounds. Prediction of Electrophoretic Mobilities in Partly Aqueous Media

Po-121 Th. Meyer, J. Böhler and A.W. Frahm (Freiburg, Germany): Determination of Cremophor EL® in Plasma of Patients after Sandimmun® Treatment

Po-122 T. Miron, L. Weiner, G. Feigenblat, D. Mirelman, M. Wilchek and A. Rabinkov (Rehovot, Israel): Development of a Direct Spectrophotometric Method for Quantitative Allicin and Alliinase Determination

Po-123 A. Moreno Gálvez, J.V. García Mateo and J. Martínez Calatayud (Valencia, Spain): Two-Simultaneous Dissolution Profiles of Pharmaceuticals in a FIA-Spectrophotometric Assembly

Po-124 N. Olgun and S. Atmaca (Istanbul, Turkey): Spectrofluorimetric Determination of Vigabatrin in Tablets

Po-125 A. Onal and A. Oztunc (Istanbul, Turkey): A Very Selective Method for the Identification and Detection of Maprotiline in Human Plasma in Overdose Using High-performance Liquid Chromatography after Derivatization with 7,7,8,8-Tetracyanoquinodimethane

Po-126 M.T. Orbey, H. Basan, N. Ertas and N.G. Göger (Ankara, Turkey): Quantitative Determination of Piroxicam in Tablets Containing Piroxicam-b-cyclodextrin by First Order Derivative Spectrophotometry

Po-127 R. Petkovska, B. Manevska, L. Petrushevska-Tozi, A. Dimitrovska and K. Dorevski (Skopje, Macedonia): AAS Method for Determination of Selenium in Therapeutical Nutritions

Po-128 P. Presits, D. Kutlán and I. Molnár-Perl (Budapest, Hungary): HPLC of Tryptophan and its Metabolites as OPA Derivatives

Po-129 I.A. Revelsky, Yu.S. Yashin, I.N. Tikhonova, A.I. Revelsky, I.N. Glazkov, V.K. Kurochkin and T.G. Sobolevsky (Moscow, Russia): Quality Control of Pharmaceuticals Based on Atmospheric Pressure Photoionization Mass-Spectrometry

Po-130 M.C. Sanfeliu Alonso, L. Lahuerta Zamora and J. Martínez Calatayud (Valencia, Spain): FIA Direct Chemiluminometric Determination of Tyrosine

Po-131 E. Sener, G. Altiokka, Z. Atkosar and M. Tuncel (Eskisehir, Turkey): Flow Injection Analysis of Meloxicam Using UV.Detection

Po-132 L. Sghendo, J. Mifsud, J.S. Millership and P.S. Collier (Malta - Belfast, N. Ireland): A Novel GC/MS Method for the Quantification of Ethosuximide Enantiomers in Biological Systems

Po-133 Zs. Skribanek and M. Mák (Budapest, Hungary): Electrospray Ionization Mass Spectrometry for the Study of Interaction between Amyloid Beta Protein and Small Molecules

Po-134 A. Szentesi, A. Gergely, P. Horváth, P. Mátyus and Gy. Szász (Budapest, Hungary): New Data About Oxime Formation by D4-3-Ketosteroids

Po-135 É. Vankó, J. Németh-Palotás, H. Köszegi-Szalai, E. Bozsik, É. Varsányi, I. Török and T.L. Paál (Budapest, Hungary): Comparative Study on the Assay Methods of Theophylline in Different Pharmaceutical Preparations

Po-136 D. Visky, M. Kraszni, S. Hosztafi and B. Noszál (Budapest, Hungary - Tiszavasvári, Hungary): HPCE Analysis of Hydrolysing Morphine Derivatives

Po-137 D. Visky, M. Kraszni, S. Hosztafi and B. Noszál (Budapest, Hungary - Tiszavasvári, Hungary): Species-Specific Hydrolysis Kinetics of Heroin and Related Compounds

Po-138 M. Yigit and L. Ersoy (Istanbul, Turkey): Determination of Tyramine in Cheese by HPLC with Spectrophotometric Detection

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D: Natural Product Chemistry and Phytotherapy: Po-139 - Po-172

Po-139 A. Altmann, D. Steinhilber and M. Schubert-Zsilavecz (Frankfurt, Germany): Natural Compounds as Nonredox Inhibitors of 5-Lipoxygenase

Po-140 R.F. Arafa (Assiut, Egypt): 3,5,7,3',4'-Pentahydroxy Flavone Antifungal Phytochemical Compound from Rumex Crispus L.

Po-141 K.K. Atindehou, E.F. Queiroz, C. Terreaux and K. Hostettmann (Lausanne, Switzerland): Antifungal Prenylated Isoflavonoids from Erythrina Vogelii

Po-142 A. Bayer and J. Stöckigt (Mainz, Germany): Search for Acyltransferases Involved in the Biosynthesis of the Antiarrhythmic Alkaloid Ajmaline Based on Approach of Molecular Genetics

Po-143 D. Bazyka, V. Klymenko, V. Tsuprikov, O. Bazyka and A. Romanenko (Kyiv, Ukraine): Immunomodulatory Effects of Uncaria Tomentosa (Willd.) DC Oxyindole Alkaloids under Low-Dose Radiation Exposure

Po-144 O. Bazyka, V. Tsuprikov, M. Illyash and D. Bazyka (Kyiv, Ukraine): Lipotropic Effect of Uncaria Tomentosa (Willd.) DC Oxyindole Alkaloids

Po-145 G. Citoglu and F. Aksit (Ankara, Turkey): Chemical Constituents of Marrubium Trachyticum Boiss.

Po-146 G. Citoglu and B. Sever (Ankara, Turkey): Diterpenoids and Flavonoids from Ballota Glandulosissima

Po-147 E. Czinner, K. Hagymási, A. Blázovics, Á. Kéry, É. Sz‘ke and É. Lemberkovics (Budapest, Hungary): Helichrysi Flos Extract, a Potential Hepatoprotective Agent with Antioxidant Activity

Po-148 B. Dános and Sz. Nyiredy (Budakalász, Hungary): Ontogenesis Investigation of Sylibum Marianum (L.) from flowering till full crop ripening, in connection with the flavonolignane content

Po-149 M.A. El-Shanawany, H.A. Hassanean, M.H. Mohamed and A.M. Nafady (Assiut, Egypt): A New Oleanene Triterpene and Hydroxy Fatty Acid from Gladiolus Segetum Ker-Gawl

Po-150 O. Gerasimova and Y. Yakovleva (Kharkov, Ukraine): Hepatoprotective Effect of the New Bioflavonoid Drug Piflamin

Po-151 H.A. Hassanean, M.S. Kamel, K.M. Mohamed, K. Ohtani, R. Kasai and K. Yamasaki (Assiut, Egypt - Hiroshima, Japan): Neolignans and Megastigmanes from Chrysanhtemum Frutescens

Po-152 M.S. Kamel, H.A. Hassanean, M.H. Assaf, K. Ohtani, R. Kasai and K. Yamasaki (Assiut, Egypt - Hiroshima, Japan): New Monoterpene Glycosides from Origanum Syriacum Growing in Egypt

Po-153 M. Kamil, A.F. Jayaraj, F. Ahmad, C. Gunasekhar, S. Samuel, K. Chan, M. Habibullah and A. Attas (Abu Dhabi, United Arab Emirates): Quality Control Studies for the Plant Rhazya Stricta

Po-154 Á. Kocsis and T. Nagy (Budapest, Hungary): Preparation of Indole Alkaloid-type Compounds from Iridoid Aglucones

Po-155 S. Kulevanova, A. Kaftandzieva, A. Dimitrovska, Gj. Stefkov and N. Panovski (Skopje, Macedonia): Antimicrobial Activity of the Essential Oils of Different Thymus Tosevii Varietes (Lamiaceae)

Po-156 Á. László-Bencsik, G. Tarján and B. Dános (Budakalász, Hungary): Essential Oil Compounds as Chemotaxonomic Markers in Wild Medicinal Plants

Po-157 O. Lopatynska and T. Kalynyuk (Lviv, Ukraine): Gingko Bilboa as a Potential Source for Homeopathic Drugs

Po-158 O. Lubinski, W. Posobkiewicz and R. Sobieska (Warsaw, Poland): Edible Mushrooms from the Forest or from Bioreactor?

Po-159 O. Lubinski, W. Posobkiewicz, P. Steckiewicz and R. Sobieska (Warsaw, Poland): Biosynthesis of Fungal Biomass from Post Fermentation Mycelium of Some Antibiotics

Po-160 E. Marchart, H. Smolnig, L. Krenn, B. Kopp, and W. Kubelka (Vienna, Austria): Investigation of Flavonoids and Caffeoyl-Derivatives in Different Species of the Achillea Millefolium Group

Po-161 K.M. Mohamed, M.S. Kamel, H.A. Hassanean, K. Ohtani, R. Kasai and K. Yamasaki (Assiut, Egypt - Hiroshima, Japan): New Acylated Flavonoid Glycosides from Bassia Muricata L.

Po-162 M.O. Odusote and I.C. Okoli (Lagos, Nigeria): Studies on Cassava Products as Tablet Diluents

Po-163 E. Sarer, A. Beyan and P.L. Schiff (Ankara, Turkey - Pittsburgh, USA): Pharmacognostic Investigations on the Thalicrtum Orientale Boiss. Alkaloids

Po-164 E. Sarer, A. Can and N. Altanlar (Ankara, Turkey): Investigation of the Volatile Oil of Vitex Castus L. and its Antimicrobial Activity

Po-165 E. Sarer, E., E. Senturk and N. Altanlar (Ankara, Turkey): Chemical Composition and Antibacterial properties of Thymus Longicaulis C. Presl. Var. Subisophyllus

Po-166 M. Szatmáry, Zs. Kiss, O. Rehák, K. Imre and É. Dobos (Budakalász, Hungary): Tendencies of Medicinal Plant Improvement in the Spirit of the EC Integration

Po-167 T. Szczepanik, K. Paradowska and I. Wawer (Warsaw, Poland): C-13 CPMAS NMR and GIAO CHF Calculations of Coumarins

Po-168 Z. Szžcs, B. Szabady, E. Fuggert, M. Szatmáry and Sz. Nyiredy (Budakalász, Hungary): Analytical Strategy for Poppy Breeding with High Alkaloid Content

Po-169 A.E. Thomas, O.A. Odukova and Adepoju Bello (Lagos, Nigeria): Physicochemical and Toxicological Activity of Hibiscus Sabdarifa

Po-170 L. Yakovleva and I. Karbusheva (Kharkov, Ukraine): Altan is a Perspective Radioprotector

Po-171 L.Yakovleva, Troshchina and A. Shalamy (Kharkov, Ukraine): Flaginat is a Prospective Reparation Drug from the Herb of Common St. John's Wort

Po-172 T. Yrjönen, O. Mousa, P. Vuorela, Sz. Nyiredy, R. Hiltunen and H. Vuorela (Helsinki, Finland - Budapest, Hungary): Influence of Operating Variables and Plant-Material Particle Size in Medium Pressure Solid-Liquid Extraction and Rotation Planar Extraction

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E: PK/PD and Toxicology: Po-173 - Po-211

Po-173 H. Akita, H. Suzuki, K. Ito, S. Kinoshita. N. Sato, H. Takikawa and Y. Sugiyama (Tokyo, Japan): Characterization of Bile Acid Transport Mediated by Multidrug Resistance Associated Protein 2 and Bile Salt Export Pump

Po-174 I. Andrys, A. Jablecka, D. Stolarczyk, A. Piotrowski, Z. Lowicki and B. Brokl (Poznan, Poland): The Assessment of Fundamental Chronopharmacokinetic Indicators of Gentamicin

Po-175 K. Balogh Nemes, Gy. Grézal, B. Dalmadi Kiss and I. Klebovich (Budapest, Hungary): Pharmacokinetic Dose Linearity Study of 200, 400 and 800 mg Acyclovir Containing Telviran® Tablets in Dog

Po-176 K. Balogh Nemes, I. Klebovich , V. Horváth, A. Tolokán, G. Horvai, P. Fekete, M. Király, J.Lehel and G. Semjén (Budapest, Hungary): Pharmacokinetic Study of a New Osmotic Release Cordaflex® Film Coated Tablet in Dog and Miniature Pig

Po-177 C. Centerholt, O. Borga, M. Ekblom, T. Odergren, G. Popescu, K.-H. Molz, A. Couturier and A. Weil (Södertälje, Sweden - Munich, Germany): An Open-Label Comparative Study of the Pharmacokinetics and Pharmacodynamics of Clomethiazole ('Zendra') in Subjects with Liver Impairment and a Healthy Control Group

Po-178 H.B. Cetin and B. Alpertunga (Istanbul, Turkey): Identification of Anticholinesterase Insecticides in Postmortem Materials

Po-179 Y.-F. Cheng, K.-G. Jostell, A. Andersson, L.B. Nilsson, M. Ekblom, S. Winsper, R. Stow, S. Morley and S. Oliver (Södertälje, Sweden - Leeds, UK - Harrogate, UK): Excretion of Radioactivity and Metabolic Pathways in Healthy Subjects Following Intravenous Administration of 14C-Clomethiazole

Po-180 R.C. Chou, S. Nick, B. Morgenroth, B. Lausecker and G. Fischer (Basel, Switzerland): Integrated Prediction of Concentration Time Profile in Man Following Oral Dosing

Po-181 M. Chrzanowska, T.W. Hermann, P. Kolecki, B. Duczmal-Cichocka and M. Górecka (Poznan, Poland): Monitoring of 6-Thioguanine Nucleotide Concentrations in Red Blood Cells of Children with Acute Lymphoblastic Leukemia

Po-182 F. Darvas and I. Szabó (Budapest, Hungary): High-Throughput Combinatorial Chemistry Combined with Predictive Tools: Application in Early Metabolism/Retrometabolism Studies

Po-183 C. Ehrhardt, J. Neumannová, U.F. Schäfer and C.-M. Lehr (Saarbrücken, Germany): Human Alveolar Epithelial Cell (HAEC) Monolayers in Primary Culture as an In Vitro- Model for Drug Transport

Po-184 S. Eksborg, N. Pal, M. Kalin, C. Palm and S. Söderhäll (Stockholm, Sweden): Pharmacokinetics of Acyclovir in Children with Leukopenia after Chemotherapy - Can Intravenous Acyclovir be Substituted by Oral Valaciclovir?

Po-185 F.K. Glówka, D. Strzelecka and S. Zapalski (Poznan, Poland): Steady-State Pharmacokinetics of Indobufen Enantiomers in Patients with Obliterative Arteriosclerosis

Po-186 N. Isoherranen, B. Yagen, M. Roeder, S. Soback, V. Schurig and M. Bialer (Jerusalem, Israel - Tübingen, Germany - Beit Dagan, Israel): Stereoselective Pharmacokinetics of Levetiracetam and its Enantiomer (R)-Alpha-ethyl-2-oxo-pyrrolidine Acetamide in Dogs

Po-187 W. Kang, O. Kuhlmann and M. Weiss (Halle, Germany): Effect of Rutin on Pharmacokinetics and Pharmacodynamics of Idarubicin in the Isolated Perfused Rat Heart

Po-188 M. Kapás, L. Gémesi, E. Terjéki, É. Kovács, É. Hajdó, M. Pátfalusi and I. Fitos (Budapest, Hungary): Pharmacokinetics and Metabolism of RGH-1756

Po-189 W. Karhan, K. Lopian, D. Behrens, W. Rieckert and B. Clement (Kiel, Germany): Reduction of N-Hydroxylated Compounds by Human Cytochrome P450 2A6, Cytochrome-b5 and NADH Cytochrome-b5 Reductase

Po-190 V.B. Larionov, V.G. Zinkovsky, I.A. Kravchenko, A.I. Alexandrova and N.V. Ovcharenko (Odessa, Ukraine): Determination of the Pharmacokinetic Parameters of the Transdermal Form of 3-Oxyphenazepam

Po-191 C. Mircioiu, M. Ionescu and D.S. Miron (Bucharest, Romania): Analytical Separation Operations as In Vitro Models for In Vivo Distribution of Drugs

Po-192 Z. Nagy, M. Kapás, B. Gachályi and J. Steiber (Budapest, Hungary): Human Bioequivalence Study of Cavinton 5mg (Gedeon Richter Ltd.) and Cavinton Forte 10mg (Gedeon Richter Ltd.) Tablets

Po-193 E. Neu, I. Gebefügl, J. Graw, G. Jackl, S. Magour, V. Foltin and M. Michailov (Rostock, Germany - Munich, Germany - Bratislava, Slovakia): Complex Changes of Signal Transduction in Mycocytes and Neuro Effector Transmission by Toxicants

Po-194 R. Oledzka and D. Skrajnowska (Warsaw, Poland): Zinc Status in Rats in the Course of Magnesium Supplementation

Po-195 G. Özhan and B. Alpertunga (Istanbul, Turkey): Genotoxic Activities of Drug-Nitrite Interaction Products

Po-196 H. Rawden and J.B. Houston (Manchester, UK): Prediction of Hepatic Clearance in Human Liver Microsomes: the Importance of Variability

Po-197 E.A. Rekka and P. Buc Calderon (Thessaloniki, Greece - Brussels, Belgium): Effect of Cold Hypoxia and Normothermic Reoxygenation on CYP3A mRNA in Cultured Precision-cut Liver Slices (PCLS)

Po-198 I.A. Revelsky, Yu. S. Yashin, T.G. Sobolevsky, I.N. Glazkov, A.I. Revelsky, A.A. Martynov and L.I. Bernstein (Moscow, Russia - Arlington, USA): Pharmaceutical Toxicity Assessment Based on the Determination of the Number and Nature of Impurities

Po-199 L. Rodrigues, A. Leal, R. Ferreira, F. Leal, M. Fernandes and P. Pinto (Lisbon, Portugal): Non-invasive In Vivo Evaluation of the Cutaneous Metabolic Activity

Po-200 L. Rodrigues, P. Pinto, A. Ribeiro, A. Gomes and L.M. Pereira (Lisbon, Portugal): PK/PD Strategies Applied to the Human In Vivo "Barrier Function" Evaluation

Po-201 S. Sahin and M. Rowland (Ankara, Turkey - Manchester, UK): Choice of the Boundary Conditions for the Axial Dispersion Model in the Analysis of Hepatic Outflow Data

Po-202 M. Sameti, C. Kneuer, U. Bakowsky, T. Schiestel, H. Schirra, H. Schmidt and C.-M. Lehr (Saarbrücken, Germany - Groningen, The Netherlands): Characterization of Complexes Based on Silica Nanoparticles and Plasmid DNA

Po-203 A. Sánchez Navarro, B. Gutiérrez Hurtado, C.I. Colino and J.M. Lanao (Salamanca, Spain): Influence of Tissue Oedema on the Distribution of Netilmicin in the Isolated Rat Lung

Po-204 D. Sugiyama, H. Kusuhara, H. Suzuki and Y. Sugiyama (Tokyo, Japan): Contribution of Organic Anion Transporter to the Net Efflux of Estradiol-17b-glucuronide from the Brain

Po-205 É. Szökö, G. Haberle, A.S. Halász, K. Tekes and K. Magyar (Budapest, Hungary): Protection by 7-Nitroindazole against DSP-4 Toxicity

Po-206 E. Terjéki, É. Hegyi, A. Juhász-Nagy, K. Galgóczy, É. Hajdó, É. Kovács, M. Pátfalusi and M.Kapás (Budapest, Hungary): Toxicokinetics of RGH-1756

Po-207 A. Tokarz, R. Oledzka, M. Jelinska and A. Czorniuk-Sliwa (Warsaw, Poland): Effects of Rape Seed, Soybean, Sunflower and Evening Primrose Oils and DMBA on Fatty Acid Composition in Rat Phospholipids

Po-208 K. Tsiakitzis, A.P. Kourounakis, Ek. Tani and P.N. Kourounakis (Thessaloniki, Greece): Effect of Alpha-Tocopherol on the Relationship between Biological and Oxidative Stress

Po-209 L. Van Obbergh, F.A. Roelants, F. Veyckemans and R.K. Verbeeck (Brussels, Belgium): Epinephrine Modifies the Absorption of Ropivacaine (R) Injected Caudally in Children

Po-210 O.V. Zhuk, V.G. Zinkovsky and N.Ya. Golovenko (Odessa, Ukraine): Modelling of Ligands and GABAA-Mediator System Interactions

Po-211 O.V. Zhuk, V.G. Zinkovsky, G.A. Tokar, M.S. Zhuk and A.V. Sivachenko (Odessa, Ukraine): Molecular Models of Receptor-Ligand Interactions for Analysis of Dynamics of Pharmacological effects In Vivo

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F: Drug Design and Development: Po-212 - Po-261

Po-212 Y. Altas, B. Berk, H. Erdogan, D. Erol and M. Özalp (Ankara, Turkey): Synthesis and Antimicrobial Activity of Some New Mannich Bases of Benzothiazole-2-thione Derivatives

Po-213 J. Apelt, H. Stark, S. Grassmann, U. Reichert, S. Elz, X. Ligneau, J.-M. Arrang, C.R. Ganellin, J.-C. Schwartz and W. Schunack (Berlin, Germany - Paris, France - London, UK): Non-Imidazole Derivatives of Reference Antagonists for the Third Histamine Subtype

Po-214 A. Balkan, U. Calis, H. Urgun, M.Z. Gören and P. Atilla (Ankara, Turkey): Some Thiazolo[4,5-d]pyrimidines as Potential Analgesic-Antiinflammatory Agents

Po-215 G. Balogh, E. Francsics-Czinege, A. Aranyi, F. Dravecz, J. Horváth, V. Dukát-Abrók and Z. Tuba (Budapest, Hungary): Isomerisation of 3-Deoxo-11-methylene-13b-ethyl-gonanes

Po-216 A. Yu. Baryshnikov, I.V. Poddubnaja, E. Lysyuk, A. Kovrigina, V. Bogatyrev, Z. Tahaev, N. Probatova and E. Sholohova (Moscow, Russia): Prognostic Markers of B-Cell Low Grade Lyphomas

Po-217 A. Yu. Baryshnikov, A.A. Sokolovskaya, D.Yu. Blokhin, T.N. Zabotina and Z.G. Kadagidze (Moscow, Russia): Programmed Cell Death and Response to Anti-Cancer Drugs

Po-218 R. Bauer, R. Lauer, B.Linz, G. Ecker, P. Friedl and C.R. Noe (Vienna, Austria): Development of an In Vitro Blood Brain Barrier Model Based on Immortalized Porcine PBMEC/C1-2 Cells

Po-219 Gy. Beke, L. Károlyházy, G. Krajsovszky, R.D. Enriz, S.A. Zacchino, F. Hernádi , P. Kovács and P. Mátyus (Budapest, Hungary - San Luis, Argentina - Sta. Fe, Argentina - Debrecen, Hungary): Pyridazine-Derivatives with Potential Antifungal Activity

Po-220 Ü. Calis, N. Gökhan and H. Erdogan (Ankara, Turkey): Synthesis and Analgesic Activity of Some Novel 3-Methyl-6-(2-substituted propanoyl)-2-benzoxazolinone Derivatives

Po-221 U. Calis, M. Köksal and T. Uzbay (Ankara, Turkey): Synthesis of Novel Hexahydropyrimidine-2,4-dione Derivatives with Potential Anticonvulsant Activity

Po-222 U. Calis, F. Özkanli, A. Güney and T. Uzbay (Ankara, Turkey): Synthesis and Anticonvulsant Activity of Some New Ethylenedioxide Derivatives

Po-223 N. Das-Evcimen, B. Pekiner, S. Süzen and E. Büyükbingöl (Ankara, Turkey): Inhibition of Aldose Reductase by Benzodiazepine Derivatives

Po-224 S. Demirayak, A. Nurzai, K. Erol and B. Sirmagul (Eskisehir, Turkey): Some Pyridazinone Derivatives and their Antihypertensive Activities

Po-225 J. Easmon, G. Heinisch, G. Pürstinger and K.-J. Schaper (Innsbruck, Austria - Borstel, Germany): Tuberculostatic Activity of 2-Benzothiazoyl Hydrazones Derived From Acylpyridine and Acetyldiazines

Po-226 P.B. Ehmer, J. Jose and R.W. Hartmann (Saarbrücken, Germany): Development of a Simple and Rapid Assay for the Evaluation of Inhibitors of Human 17alpha-hydroxylase- C17,20-lyase (P450c17) by Co-expression of P450c17 with NADPH-cytochrome-P450-reductase in Escherichia Coli

Po-227 G.A. El-Gindy (Assiut, Egypt): The Interaction of Furosemide with Heptakis(2,6-di-O- methyl)-b-cyclodextrin in Solution and Solid State

Po-228 O. Éliás, L. Károlyházy, G. Stájer and P. Mátyus (Budapest, Hungary - Szeged, Hungary): Synthesis of Novel Fused Pyridazines

Po-229 R. Gáspár, A. Márki, E. Ducza and G. Falkay (Szeged, Hungary): Comparison of the Effect of Terbutaline and Subtype Selective Alpha1-Adrenoceptor Antagonists of Pregnant Rat Uterine Contractions In Vitro

Po-230 J.F. Gilmer, L. Moriarty, M. Lally, J.M. Clancy (Dublin, Ireland): Inter-Species Variation in the Hydrolysis of a Novel Nitro-Aspirin

Po-231 J.F. Gilmer, L. Moriarty, M. Lally, J.M. Clancy (Dublin, Ireland): Synthesis and Kinetic Studies on Salicylate Metabolites of Isosorbide Diaspirinate

Po-232 P. Heinonen, J. Rosenberg and H. Lönnberg (Turku, Finland): Synthesis of Achiral aa-Bis(aminomethyl)-b-alanines, and their Use in Preparation of Branched b-Peptide Conjugates on a Solid Support

Po-233 F. Herold, D. Maciejewska, M. Pisklak and I. Wawer (Warsaw, Poland): C-13 CPMAS NMR Studies of Novel 4-Aryl-hexahydro-1H,3H-pyrido[1,2c]pyrimidine Derivatives

Po-234 I. Isikdag, U. Ucucu, N. Gündogdu, A. Meric, Y. Öztürk, S. Aydin and B. Ergun (Eskisehir, Turkey): Synthesis and Antispasmodic Activity of Some 2- and 1,2-Disubstituted 4,5,6,7-Tetrahydro Benzimidazoles

Po-235 I. Isikdag, Ü. Ucucu, A. Meric, N. Gündogdu Karaburun, S. Aydin and B. Ergun (Eskisehir, Turkey): Synthesis, Mutagenicity and Analgesic Activity of Some Tri- and Tetraisubstituted Imidazole Derivatives

Po-236 M. Jadrijevic-Mladar Takac and I. Butula (Zagreb, Croatia): A New Route to Substituted N-Hydroxyurea Derivatives

Po-237 M. Jadrijevic-Mladar, D. Vikic-Topic, B. Zorc and M. Kranjec (Zagreb, Croatia): Spectroscopic Study of Fluoroquinolone Complexes with Metal Ions

Po-238 M. Karaivanova, I. Kostova, I. Manolov and I. Nicolova (Sofia, Bulgaria): New Lanthanide Complexes of Coumarins and their Pharmacological Activity

Po-239 Y.N. Khomyakov, A.V. Nadezhkina, L.N. Kryukov, E.A. Vorontsov, L.Y. Kryukova, I.I. Krylov, S.L. Kuznetsov, A.S. Dukhanin, I.N. Yankin, I.E. Zykova and S.E. Severin (Moscow, Russia): New Strategy of Anticoagulant Design and Development: Synthesis and Evaluation of Antithrombotic Potential of Quinoline Derivatives

Po-240 P. Komárek, I. Kleisner, I. Komárková and M. Konopková (Prague, Czech Republic): Photoactivation-formed SH Groups of Proteins and their Labelling with 99m Tc by Direct Method

Po-241 Zs. Lázár, L. Lénárd jr., R. Benkó, G. Tóth, B. Penke, J. Szolcsányi, C.A. Maggi and L. Barthó (Pécs, Hungary - Szeged, Hungary): Evidence for the Involvment of P2 Purinoceptors in the Excitatory Effect of Capsaicin in the Small Intestine

Po-242 N.B. Leonidov, S.I. Uspenskaya and V.V. Gatsura (Moscow, Russia): Modern Approaches to Azidothymidine Therapeutic Effect Intensification

Po-243 T. Librowski, R. Czarnecki, M. Pasenkiewicz-Gierula, J. Grochowski, P. Serda, S. Lochynski and B. Frackowiak (Cracow, Poland): Multidisciplinary Studies of Chiral Carane Derivatives with a Strong Local Anaesthetic Activity

Po-244 A. Meric and Z. Seller Incesu (Eskisehir, Turkey): Synthesis of Some 2,4-Disubstituted Benzimidazo-[1,2-a]pyrimidines and 3H-2,3-disubstituted Benzimidazo[1,2a]imidazoles and Studies on the Cancer Cell DNA and Proliferation of Cancer Cells

Po-245 P.I. Nagy and B. Noszál (Toledo, USA - Budapest, Hungary): Theoretical Study on the Tautomeric/Conformational Equilibrium of Aspartic Acid Zwitterions in Aqueous Solution

Po-246 N. Oborotova, B. Cheltsov, B. Kikotj, A. Polazkova, L. Gatinskaya, E. Ignatieva, N. Dmitricheva, O. Orlova and G. Gerasimova (Moscow, Russia): Development of New Antineoplastic Drug Formulations from Platinum and Copper Complexes

Po-247 D. Oehler, C. Orth, J.W. Bats, A.S.K. Hashmi, W. Strauss and M. Schubert-Zsilavecz (Frankfurt, Germany - Ulm, Germany): Nonsteroidal Antiprogestins as a Basis for the Development of New PDT Drugs

Po-248 F. Pour-Morad, A.R. Dehpour and S. Sahraee (Sari, Iran - Tehran, Iran): Comparison between Anococcygeus from Control and Streptozocin Diabetes Rats

Po-249 A. Sasse, G. Meier, B. Sadek, X. Ligneau, S. Elz, C.R. Ganellin, J.-M. Arrang, J.-C. Schwartz, W. Schunack and H. Stark (Berlin, Germany - Paris, France - London, UK): Derivatization of the Oxime Funcionality of Imoproxifan, a Highly Potent Antagonist of the Third Histamine Receptor Subtype

Po-250 O.B. Seregina, S.I. Uspenskaya and N.B. Leonidov (Moscow Russia): Primary Evaluation of Biological Activity of Polymorph Drug Modifications on Protozoa

Po-251 V. Simkeviciene and Cekuoliene (Vilnius, Lithuania): Antitumor Activity of Some Compounds Containing Nitrogen

Po-252 L. Simon, L. Lázár and F. Fülöp (Szeged, Hungary): Synthesis of Novel 5-Alkyl-7,8-dialkyloxyisoquinolines

Po-253 É. Szárics, I. Kovács, N. Skuban, J. Almási, K. Takács-Novák, J.Kökösi, B. Noszál and J. Kardos (Budapest, Hungary): Differential Effects of 2-Methyl-4-oxo-3H-Quinazoline Alkyl Carboxylic Acid Homologues on the Trans-Membrane Calcium Ion Influx Mediated by Different Glutamate Receptor Subtypes in Rat Brain

Po-254 E. Tarasevicius and Zitkevicius (Kaunas, Lithuania): Synthesis and Biological Evaluation of Novel Substituted Sulfanilamides

Po-255 K. Tekes, G. Faludi and E. Dinya (Budapest, Hungary): Prediction of Response to Fluvoxamine in Panic Disorder Patients

Po-256 A.V. Thopchyan, R.S. Mirzoyan, M.G. Balasanyan, N.A. Semeonova and G. Ulikchanyan (Yerevan, Armenia): Lactate Level Alteration in Rat Ischemic Brain in Response to a New Drug Combination

Po-257 K.A.Toibaeva and N.A. Ajtkhozhina (Almaty, Kazakstan): Improved Strategy for the Practical Use of Colchicine

Po-258 G. Turan-Zitouni, Y. Blache and K. Guven (Eskisehir, Turkey - Montpellier - France): Synthesis and Antibacterial Activity of Some Imidazo[1,2-a]pyridine-2-carboxylic Acid Arylidinehydrazide Derivatives

Po-259 Ü. Ucucu, I. Isikdag, N. Gündogdu Karaburun, A Meric, Y. Öztürk, S. Aydin and B. Ergun (Eskisehir, Turkey): Synthesis and Antispasmodic Activity of Some 2,5-Di- and 1,2,5-Trisubstituted Benzimidazole Compounds

Po-260 A. Yesilada, B. Asal, E. Büyükbingöl, E. Yildirim and K.Erol (Ankara, Turkey - Eskisehir, Turkey): Antinociceptive and Antidepressant Effects of the Stereoisomers of a Synthetic Dipeptoid Analog of Cholecystokinin

Po-261 M. Zovko, B. Zorc and M. Jadrijevic-Mladar Takac (Zagreb, Croatia): Synthesis of Fenoprofen Prodrugs

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G: Regulatory, Validation and Other Issues: Po-262 - Po-271

Po-262 M.H. Borawska, A.M. Witkowska, A. Kuryliszyn-Moskal and K. Hukalowicz (Bialystok, Poland): Soluble Endothelial Cell Adhesion Molecule (sICAM-1), Selenium and Diet in Rheumatoid Arthritis

Po-263 Á. Mészáros, P. Magyar and Z. Vincze (Budapest, Hungary): Health Related Quality of Life and Asthma

Po-264 M. Michailov, G. Govil, W. Jaud, E. Neu, W. Schneider, J. Schröder (Munich, Germany - Mumbai, India - Innsbruck, Austria): Pharmacy between Medicine and Ecology: International Education and Research Programmes

Po-265 B. Noszál (Budapest, Hungary): Advances in Drug Chirality

Po-266 G. Olguner, A.Y. Özer, M. Özalp and A.A. Hincal (Ankara, Turkey): Terminal Sterilization of Antibacterial Drugs II: Sulphonamides

Po-267 J.A. Orwa, E. Roets and J. Hoogmartens (Leuven, Belgium): Investigation of Stability of Polymixin B1

Po-268 L. Rodrigues, J. Tavares, R. Minhós, J. Serra, J. Pereira, L. Gouveia and P. Pinto (Lisbon, Portugal): Quantification of the Relative Contribution of Human Epidermis to the Cutaneous Biomechanical Behaviour

Po-269 Zs. Szepezdi, L. György and É, Csekey (Budapest, Hungary): Drug Consumption in Hungary 1990-1998

Po-270 S. Trajkovic-Jolevska, I. Stojanovska and A. Dimitrovska (Skopje, Macedonia): Adoption and Implementation of ICH Guidlines into Regulatory Issues in the Republic of Macedonia

Po-271 C.-C. Zammit, M.A. Sant Fournier and A. Zahra (Malta): Comparative Moisture Permeation for Tablet Containers

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