M Rowland BPharm PhD DSc(London) DSc(Hons,Poitiers) DPh(Hons,Uppsala) MSc(Manchester) FRPharms FIMA Tel: +44 (0)161 275 2348 FAX: +44 (0)161 273 8196 E-mail: MRowland@fs1.pa.man.ac.uk

Research
Pharmacokinetics
Physiological Modelling
Interspecies Scaling
Quantitative Structure Pharmacokinetic Relationships
Intestinal Drug Absorption

Recent Publications
Blanchard, J., Tozer, T., and Rowland, M. Pharmacokinetic perspectives on megadoses of ascorbic acid. Am. J. Clin. Nutrition. 66: 1165-1171 (1997)
Blakey, G.M., Nestorov, I.A., Arundel, P.A., Aarons, L.J., Rowland, M. Quantitative structure-pharmacokinetics relationships: I. Development of a whole-body physiologically based model to characterize changes in the pharmacokinetics across a homologous series of barbiturates in the rat. J. Pharmacokin. Biopharm. 25: (3) 227-312 (1997).
He, Y-L, Murby S., Warhurst, G., Gifford, L., Walker, D., Ayrton, J. Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of polyethylene glycol and D-peptides. J. Pharm. Sci. 87: (5) 626-633 (1998)
Oliver, R.E., Jones, A.F., Rowland, M. What surface of the intestinal epithelium is effectively available to permeating drugs? J. Pharm. Sci. 87: (5) 634-639 (1998)
Nestorov, I., Aarons, L.J., Arundel, P.A., and Rowland, M. Lumping of whole body physiologically based pharmacokinetic models. J. Pharmacokin Biopharm. 26, (1) 21- 46 (1998).
Kawai, R., Matthew, D., Tanaka, C., and Rowland, M. Physiologically-based pharmacokinetics of cyclosporine A: Extension to tissue distribution kinetics in rats and scale-up to human. J. Pharmacol. Expt. Therap. 287: 457-468 (1998)

Teaching
Principles of Pharmacokinetics
Clinical Pharmacokinetics
Main organiser of Basic and Advanced residential courses in Pharmacokinetics

Current Positions
Professor and Head, School of Pharmacy
Director, Centre for Applied Pharmacokinetic Research
Member, Board of Directors, Medeval Ltd.
President, European Federation of Pharmaceutical Scientists (EUFEPS)
Editor, Journal of Pharmacokinetics and Biopharmaceutics.
Member, Editorial Advisory Board of Journal of Pharmacological and Toxicological Methods, Journal of Physiological Society, Advanced Drug Delivery Reviews.

FUTURE WORKSHOPS IN ASSOCIATION WITH PROFESSOR M ROWLAND

Further information on the Basic Pharmacokinetic Workshop, July 2001, Arosa, is available as a pdf file.